| Year | Milestones |
| 1924 | Establishment of Lytton Medical School |
| 1962 | Upgrading of Lytton Medical School to Mymensingh Medical College. |
| 1970 | Indoor Service of Mymensingh Medical College Hospital started |
| 1972 | Shifting of college to the present campus |
| 1979 | Inception of department of Orthopaedics |
| 1981 | Inception of Family Planning Model Clinic in the hospital |
| 1988 | Inception of department of Cardiology |
| 1992 | Establishment of Centre for Nuclear Medicine & Ultrasound Departments of Microbiology & Biochemistry began their activities as separate departments |
| 2000 | Diploma in Child Health (DCH) was started as the first Postgraduate course. Inception of departments of Neuromedicine, Neurosurgery, Nephrology, Endocrine Medicine & Paediatric Surgery |
| 2002 | 27 Postgraduate courses (MD, MS, MPH, M Phil, Diploma) began to run under the auspices of the present government Mymensingh Medical Journal was indexed in Index Medicus, MEDLINE & Pub Med and began to be available online in the USA & throughout the world |
| 2003 | Internet was introduced & whole college came under a local Computer Network |